My name is Joshua Porch and at the time of this writing I'm 30 years old. I may have gotten a Bachelor's Degree in Communication Art and Design from Lee's McRae College in 2014, but science has been my true passion since I was a little kid.
For the past 16 years, I've been studying biology, chemistry, psychology, pharmacology, ethnobotany and ethnopharmacology, as well as philosophy, quantum physics, and seeking to understand the workings of the spiritual world (as a Christian who believes that supernatural events are a regular part of everyday life.)
I'm striving to teach people the science of how the body works, and how they can use food and plants to enrich their quality of life and reduce or eliminate many health issues from their lives.
Hi there everyone, my name is Joshua Porch and I’m the founder and CEO of Bio Hacking Academy. I know I haven’t been active for a while, life has just had me way more busy than I thought I’d be during this pandemic period.
I’ve been promising for a while now that I’d do a review on CBG-A since I already did a review on regular CBG. If you guys don’t already know, CBG-A is the acid form of CBG, which occurs naturally within the plant. Nearly all cannabinoids exist within the plant in their acid forms until after the plant has been harvested and dried, and even then most of the cannabinoids remain in their acid form until they are heated either by flame, oven, dry herb vaporizer, etc.
Why does this matter? Because with most cannabinoids, the acid form has far different effects than the non-acid form of that cannabinoid (also called it’s decarboxylated form). Well, when I made and tried some CBG-A tincture, I was very surprised by what I found. The effects of CBG-A were not much different than the effects of CBG. With things like CBD-A or THC-A, those compounds have very different effects than CBD and THC, respectively.
What I discovered with CBG-A is that I got just as much relaxation, calmness, improved vision and drowsiness from it as what I get from regular, decarboxylated CBG. This was so strange to me since like I said before, the effects of CBD-A are pretty opposite of the effects of CBD. Same with THC-A vs THC.
Really, I can’t tell you whyCBG and CBG-A seem to behave in a different manner inside the body than the other cannabinoids, but it is quite interesting. I don’t have much more to say about it other than that CBG is proving to be a more useful cannabinoid (from a medicinal standpoint) than people once thought.
I’ll always be adding in some Hemp related reviews on a fairly regular basis, but I think I’m going to pause that for a little while and teach on some other types of plants, nutritional supplements and lifestyle techniques to improve your quality of life.
If you haven’t subscribed to follow my blog and Facebook page, please do so you’ll be most up to date on all the newest content I put out. Stay tuned for more, coming soon.
Hey everyone, WELCOME to the Bio Hacking Academy. I’m your host and educator, Joshua Porch, and today we’re going to be discussing CBG. The CBG I’m going to be referring to here today comes from legally grown industrial hemp, and is fully compliant with federal regulations here in the USA. This video is intended for viewers 18 years or older and does not endorse or condone any illegal or dangerous activity.
So, with that out of the way, I’m first going to explain briefly what CBG is (for those of you who don’t already know what it is) and then I’m going to dive into the chemistry of how it works, what affects it has on the body and mind, and how YOU or someone you know can take advantage of CBG and use it to enhance your (or their) quality of life!
So, to start, CBG (in it’s naturally occurring acid form called CBG-A) is the primary compound present in all cannabis plants up until the last few weeks of the Flowering phase, which is also known as the last few weeks before the buds have reached maturity and are ready for harvest. CBG-A is then converted into THC, CBD, or other minor cannabinoids, most of them in their acid form. However, new varieties of industrial hemp have been developed which are intended to produce CBG almost exclusively, and the plant is harvested at the ideal time for CBG content.
Now, the CBG remains in it’s acid form (CBG-A) until the plant material goes through the process called “Decarboxylation”, also called “Decarbed” for short. When the hemp is cured and dried, some of the CBG becomes decarbed, but most will remain in the acid form until it is heated, through baking in an oven at the right temperature for the right amount of time, vaporized or smoked. I will try out CBG in it’s natural, acid form and make a separate review on it. But for this review, I’m talking about regular CBG.
Ok, so what does CBG DO? Well, first I need to ask, have you ever tried CBD before? Do you know what it feels like? If you answered yes, then try to imagine a combination of CBD and Valium, or CBD and Lavender. That is what CBG feels like in your body, but CBG simultaneously gives you a clear headed, energized mind.
If you’ve never tried CBD before and don’t know what it’s like, well then you can just think of CBD and CBG as producing a very relaxing tingly sensation on your skin, and the experience is sometimes mildly euphoric, but not always.
Now, on to discussion of what it’s good for.
Most people who use CBG consider it excellent for reducing anxiety and depression, even more effective for those health problems than CBD. In my personal experience, it offers better pain relief than CBD but less than Delta 8-THC or Kratom. I will make a video about Delta 8 soon, and I’ve already written an article about Delta 8 on my website, and I did a Kratom review video several months or more ago.
I find CBG most beneficial mid day and in the evening, but not immediately before bed. CBG can make you slightly sleepy, but for the most part it is mentally energizing until it starts wearing off. I think CBG would be great to use right before working on projects, homework, computer work, watching videos, writing, or any other activity that requires sustained focus and maintaining a calm countenance throughout.
I have also found that mixing equal parts of CBD and CBG is a wonderful combination, providing many of the same benefits of regular THC/Marijuana, while avoiding most of the negative side effects that often come from THC. Now, so this is a well balanced review, I will give some warnings, and then I’ll share some good, trustworthy sources of CBG products so that you can get some and try it for yourself.
I really don’t have that many warnings about CBG. However, since it does increase activation of the GABA receptors, it can slow breathing and should not be combined with other sedatives in most situations. CBG also increases endorphin release (though activation of the CB2 receptor) and this may cause drowsiness, so don’t take CBG before driving, operating heavy machinery, or doing any other activity which could be dangerous without proper alertness. If you choose to do so anyway, you do so at your own risk and not at my advisement. CBG may also lower blood sugar levels and may also lower blood pressure, so keep that in mind if you choose to try CBG.
Now, let’s talk about some good quality CBG products and where to purchase them.
“White Tiger” CBG Hemp Flower – 20% CBG Sativa-Leaning Hybrid from Loud House Hemp Company. Select “White Tiger @ 20% CBG” from the drop down menu.
CBG oil from Flower Child CBD Company (the only full spectrum CBG oil I could find anywhere). This one, WordPress is saying has an error with trying to embed the link, so copy and paste the URL into a new tab if it does not appear as a clickable link for you, so that you won’t lose your place here on this page…. stupid WORDPRESS! If the link does work, please still right click it and select “open in new tab” so you won’t lose your place here.
“New Dawn” CBG oil from Industrial Hemp Farms. This appears to be a CBG isolate dissolved in an oil, and this will not be as effective as using Full Spectrum CBG, but it will be a pure CBG experience nonetheless.
American Shaman and Extract Labs (along with most other results I found) offer oils that have CBD & CBG combined, usually in a 1:1 ratio. This may be a nice combo but they are not CBG alone. WordPress is ALSO giving me an error message with Extract Labs’ link (which is the second one below that just says “CBG Oil”, so if that one isn’t clickable for you, copy and paste it into the URL bar in a new tab so you won’t lose your place here on this page. If the link does work, please right click it and select “Open in New Tab” so that you won’t lose your place here.
Now I need to mention one more important point before I go… DOSAGE!
In my opinion, CBG is more potent than CBD, but not everyone may agree with that. However, I think that 1 to 2 milligrams (mg) of CBG is a good starting dose for most people. If using a CBG oil, you can determine 1-2 mg by dividing the total number of milligrams of CBG in the entire bottle by how many milliliters (mL) of oil are in the bottle. This will tell you how many milligrams of CBG are in each milliliter of oil. Then, divide the number of mg’s of CBG in 1 mL of oil by 30, and that will give you a pretty close estimate of how many mg of CBG are in each drop, because most of the time, 30 drops from an eye dropper equals 1 mL of liquid.
I know that may sound like a lot of trouble to a lot of people, so to make it easier, just try 2-3 drops of your chosen CBG oil when first trying it out.
Alternatively, you can get a dry-herb vaporizer (like the Sutra Mini, which is an excellent choice) and use it to vape some CBG flower. The Sutra Mini can be found here:
Most CBG flower on the market today is between 8% to 20% CBG. I would suggest everyone who decides to Vape or Smoke CBG flower to start off with 25 mg of flower, and see if that is good or if you need more. People who currently use THC will need to use a lot more CBG to feel it’s effects compared to people who only use CBD regularly or someone who does not use any cannabinoids regularly.
If Vaping CBG flower, set the temperature on the Vaporizer to 430 F to make sure that ALL of the CBG gets vaporized out of the flower material and into your lungs. CBG’s boiling point or evaporation point is 428 F and while you can get SOME CBG at lower temperatures, most of it will not come out into the vapor until you reach at least 428 F.
Alright, that about does it for this article. I hope you’ll be intrigued by this article and give CBG a try. If you do decide to try it out, come back to this video and let me know what you thought about CBG.
Until next time,
God Bless You, and Have a Great Day!
– Joshua Porch, Founder and CEO of Bio Hacking Academy
Delta 8-THC is one of the newest natural cannabinoids on the block, and it boasts more medicinal benefits than CBD and less psychoactivity than the regular ol’ THC found in Marijuana, which is called Delta 9-THC. Delta 8 is naturally occurring in marijuana and hemp plants, however it is a trace compound in everything except very old marijuana that has sat out in the sun and heat for a long time. However, both traditional, regular ol’ THC and CBD can both be converted into Delta 8 through various refinement processes. Because of the way the 2018 Farm Bill was written, if Delta-8 or the CBD that is used to produce it is present in Industrial Hemp plants that are grown in a legal, licensed manner, then that resulting Delta 8 and every other cannabinoid present in the hemp is considered legal to possess, use, sell or distribute as long as the Delta 9-THC content is below 0.3% of the hemp or hemp preparation on a dry weight basis.
Thus, Delta 8 is legal on a federal level as long as it is derived from industrial hemp plants that were grown by a licensed grower in accordance with federal and state regulations. However, there are several states that have made Delta 8-THC illegal or made it available only by prescription, even though it is legal under Federal law within the confines of the 2018 Farm Bill. However, in my state of North Carolina, and in nearly 40 states, hemp derived Delta 8 is legal to buy and use.
Delta 8-THC, despite it’s name, is technically an isomer of CBD, not THC. While Delta 8 shares structural similarity to regular THC, it’s effects are more like a mixture of those of CBD and THC, with a little bit additional unique attributes to it that you won’t get from either CBD or regular THC (that is, Delta 9-THC, the main psychoactive cannabinoid in marijuana).
Delta 8-THC WILL make you test positive for regular THC on a drug test, and the only way to clear yourself if this happens is to have the test sent off to be further analyzed to prove that the metabolites did not come from Delta 9-THC (which is the illegal form). So, with that in mind, use Delta 8 at your own risk. That is in reference to employment drug testing. DO NOT use Delta 8 if you are on probation or have to pass a drug test as part of your medical care, because they will not give you the time of day to prove yourself to them that you did not consume an illegal product. You will be arrested or cut off from your prescription drug therapy in such cases due to the evil and corruption in today’s legal and medical systems.
Delta 8-THC has been shown by many people to possess all of the same medicinal benefits of CBD and THC, except that it causes less mental alteration than regular THC found in marijuana (Delta 9-THC). Delta 8 has been shown to be more effective than traditional THC in treating/preventing nausea and vomiting, and it was even given to children in considerably high doses in clinical trials with far less negative side effects than what are reported from regular Delta 9-THC and manmade prescription anti-nausea drugs. This was regarding children with cancer who were undergoing chemotherapy, studies done in Israel by world renowned cannabinoid researcher and scientist Raphael Mechoulam and done in conjunction with various medical centers, doctors and scientists. Mr Mechoulam also reports on nearly 500 cases of Delta 8 THC being used to treat cancer, either by killing all of the cancer cells or by greatly reducing the size of the tumors and slowing their growth. Delta 8-THC is reported to be effective for treating a variety of types of pain, as well as helping reduce or temporarily eliminate anxiety, depression and insomnia in SOME people, as well as helping some people suffering from IBS and other bowel problems.
I only found out about Delta 8 a few weeks ago (as of the time of writing this), and while I was nervous to try it and unsure whether I wanted to, a new health problem I was having had been going on for about a week or more already right around the time I heard of Delta 8. This pushed me to the point where I either had to get on a prescription drug that is expensive and laden with regulation and red tape, OR find a natural solution that could fill it’s place.
I first saw Delta-8 THC listed on a CBD Hemp supply store that I receive texts on my phone from. I ordered a vape cartridge, the brand/manufacturer was called “Alt Cannabinoids”. It wasn’t filled with e-liquid… I don’t do that kind of vaping anymore. This was filled with Delta 8 distillate, which is a very thick, highly purified resin that is vaporized from the same kind of “pen” that’s used for regular e-cig cartridges. I got mine for about $20, and it came with a couple of attachments which I didn’t use or used improperly and had to throw away.
Before buying the Delta 8, I researched a lot to see what it’s like. I’m VERY sensitive to regular THC, and knowing that the Delta 8 extract cartridge was 92% Delta 8-THC content, I was concerned that even one hit (inhalation) would be too strong, because I don’t like the feeling that I’ve gotten in the past from too much regular ol’ THC like you get from weed or prescription dronabinol pills (which I used to have a prescription for which lasted several months, but they caused more problems than what they helped).
Anyway, what I found out about Delta 8’s effects in comparison to CBD and regular Delta 9- THC was that Delta 8 WAS psychoactive (ie it can get you high) but in a gentler, milder, easy going way compared to regular THC (Delta 9) which can cause paranoia and anxiety in too high of a dosage. I learned that Delta 8 had a stronger effect than CBD but that it was just right for most people’s needs, and provided a sharper mind and improved cognition compared to regular Delta-9 THC.
I decided to be very cautious when I got the cartridge in the mail about a week later. I plugged it up to my vape pen and took one small and brief puff, like 1/4 of a second long. It had virtually no taste or smell, and it didn’t have any terpenes (essential oil compounds) or flavorings added to it. The effect was very quick to first come on, and I noticed first a sharpening and brightening of my vision. The effects built over the next 10 minutes or so, and while it wasn’t TOO STRONG, it was stronger than I expected or even necessarily wanted. It took a little getting used to. The physical feeling I got in my body was pretty much identical to the feeling I get from regular THC or higher doses of CBD.
Anyone who has experienced cannabis before knows what I’m talking about. If you’ve never tried it before, it’s a strange tingly, electrical/vibration type of sensation that covers your skin and also seems to buzz around in the air around your body. If you’re reading this and have never consumed any type of marijuana or hemp products, then please start with CBD. CBD is milder than Delta 8-THC, while regular Delta 9-THC is stronger still. Delta 8 is for people who do not get adequate pain relief, nausea relief or relaxation from CBD alone. If you feel that you need or want to try Delta 8, I’d suggest taking some CBD before the Delta 8 to give you a better “entourage effect” and make it calmer from a psychological standpoint in case you accidentally overdo it on the dosage of Delta 8. Only once you’ve tried Delta 8 with CBD a few times should you try raising the dose of Delta 8 or consuming it solo, without CBD.
That warning goes for people who are newbies to cannabis or have only used CBD. For people who are used to using regular marijuana/Delta 9-THC, Delta 8 will seem much calmer and chill to them right from the beginning. I just want to make sure that all people of all backgrounds know how to use Delta 8 safely if they choose to try it.
So, what are the benefits I’ve received from taking Delta 8?
Well, for starters, I need to state that what I have felt from it thus far may be a little bit different than what most people feel, because I have Kratom in my system 24/7 pretty much, though some parts of the day the amount of Kratom in my bloodstream is too low to notice. I have tried Delta 8 along with my normal dose of Kratom, and I’ve also tried Delta 8 when the Kratom was at too low of a level for me to notice. I also have caffeine in my system most of the day so that can also affect my Delta 8 experience, though I have tried Delta 8 when caffeine has been high and very low in my system so I can compare those as well.
With all of that being said, in general, Delta 8 feels similar to traditional Delta 9-THC and CBD in regards to the tactile feeling it produces in your body and the way they all affect your vision… at least at first. The feeling changes part of the way through. You see, Delta 8 starts off feeling like a cross between regular THC (that is, Delta 9 THC) and CBD, however, depending on the method of administration that you used, how long this feeling lasts can vary. Inhaled or topical/transdermal (through the skin) methods of taking Delta 8 feel more like regular cannabis than taking it orally as an edible oil or in food. Either way, at some point the typical “cannabinoid” type of feeling in your body fades away and transitions into a very soft, warm, fuzzy feeling that is very similar to what you get from opiates. I will explain why this happens in a minute, but it is nothing to fear.
While some people like the typical “cannabinoid” feeling in their body and mind, I find the opiate-like feeling more comfortable and better suited to helping my particular ailments, most of the time, while too strong of a “cannabinoid” feeling in my body can cause anxiety for me… and this can happen even from high doses of CBD. Anyways, when Delta-8 transitions over to producing the opiate-like feeling, it does so because Delta 8 activates the CB2 receptor, which lab studies (in mice) have shown to cause a release of endorphins (beta-endorphin to be precise). Endorphins are a naturally occurring opioid compound that our bodies create and release during different activities. Endorphins are released during exercise, after a major stressful event has subsided, during and after sex/masturbation/orgasm, during eating good tasting food, etc. Endorphins are usually released inside the body at the same time as Anandamide, which is a naturally occurring cannabinoid-like compound in our body. Both are usually active at the same time, and the combination of their effects explains at least some of the cause behind naturally occurring euphoria (ie not drug induced).
So, because Delta 8 activates the CB2 receptor in addition to activating the CB1 receptor (which regular Delta 9-THC does), and because activating the CB2 receptor releases endorphins, as the activity at the CB1 receptor fades and the CB2/endorphin activity remains for a while longer, that’s what produces that opiate-like feeling that Delta 8 transitions into.
When Delta 8 transitions over into this opiate-like feeling, it makes the eyelids feel heavy, and it can induce a slight “nod” just like regular opiates do, depending on how high of a dose you’ve taken. Because I take Kratom too, I get a stronger opiate-like feeling from Delta 8 than most people will who take Delta 8 on it’s own, by itself.
After I’d tried out the Delta 8 vape cartridge for a while, I found a site selling some Delta 8 in oral form, in the form of an oil… like CBD oil, but it was just Delta 8 dissolved in Coconut Oil. I have experimented with this and while I do like it, it is much more mild and more opiate-like in effect than inhaled or topical Delta 8. Once you’ve been vaping Delta 8 or applying it to your skin (dissolved in oil or alcohol) for a few days straight, and then you try taking it orally, the your tolerance to it’s effects is much higher right from the get-go and it’s affects are much milder and slower to kick in. Doing it this way may produce a bit of that standard cannabinoid feeling for a little while, but for the most part it’s similar to CBD oil or a low dose of codeine. This can be advantageous in some situations where the typical cannabinoid type of feeling would be unwelcome but you still need the medicinal benefits that Delta 8 has to offer. When combined with caffeine, the result is a calm, warm and fuzzy and relaxed feeling with enough energy and mental clarity to successfully knock out most tasks that people would face day to day. However, I would not recommend driving under the influence of Delta 8 until you are VERY used to it’s affects and will not be consuming intoxicating quantities close to the time you plan to get behind the wheel.
Delta 8 DOES produce tolerance rather quickly, though the tolerance to it’s “weed-like” effect develops much faster than tolerance to it’s more soft and fuzzy opiate-like effect. When you still feel the opiate-like effect but no longer feel the “weed-like” effect from it, you’ll know that you may need to increase your dose just a little or stay where you are a little longer if you prefer the gentle, opiate-like feeling. However, if you stay at the same dose long enough, the soft and fuzzy feeling will eventually go away too. Once you no longer feel anything at all from a dose, that’s when it’s time to increase your dose or take a break for several days or more to reset your tolerance.
Now, I need to post some warnings.
First of all, higher doses of Delta 8-THC can temporarily raise your blood pressure and heart rate because of the speedy, rushing effect that larger doses will produce, just like regular Delta 9-THC from marijuana. This effect tends to only last for about 10-20 minutes and then your blood pressure will actually begin to lower below it’s typical level. Lower and medium doses of Delta 8 that do not feel intense will lower your blood pressure pretty much right from the get-go. This happens because Delta 8-THC causes your body to increase production and release of Acetylcholine, which expands your blood vessels and lowers your blood pressure. Delta 8 also lowers your blood pressure and expands your blood vessels by opening up potassium channels, which will increase your blood potassium and lower your sodium/potassium ratio. Also, lower and medium doses of Delta 8 can lower your blood sugar too, just like CBD can do. So, if you plan to consume CBD and/or Delta 8-THC, be sure to have some medium or high glycemic carbs (something not high in fiber) and something salty. If you start feeling light headed, consuming some carbs and salt should make you feel better. CBD and Delta 8 may also block calcium channels, and this could contribute to some of the negative side effects that can arise from higher doses of CBD and/or Delta 8-THC. So, consider adding some dairy or some food source of calcium to the list of foods to consume if you start feeling light headed when using CBD or Delta 8.
Because of these mechanisms of action (the potassium, acetylcholine and blood sugar effects), people should not use Delta 8-THC or even CBD for that matter in conjunction with ACE-inhibitors, sodium channel blockers, or any other drug that lowers blood pressure or blood sugar. If you take these kinds of medications and you STILL want to try CBD or Delta-8, use caution and start with a very low dose of CBD or Delta 8 to see how it affects you in conjunction with your medications. If you have a doctor who is well educated in the science of cannabinoids or is friendly to your use of them, then I would advice speaking to them about your plans to use CBD or Delta 8, and ask them to listen to you for feedback and look into possibly altering your dose of prescription medication to accommodate for the effects blood pressure, blood sugar, and potassium/sodium related effects of CBD or Delta 8. Print this article out, highlight this section and take it with you to the doctor if necessary to ensure that he/she gets the right info about the pharmacology of CBD and Delta 8-THC.
The next warning applies more to inhaled or skin-applied Delta 8, but it could also apply to edible forms. When you take Delta 8-THC via inhalation or apply it to your skin through a rapidly absorbed medium like alcohol or MCT oil, it feels almost identical to traditional Delta 9-THC that is found in marijuana, with the only exception being that there are LESS mental affects such as confusion and paranoia. Because inhalation and topical/transdermal use can produce a feeling very similar to regular THC, it is important to be careful about your dosage, because taking even a little bit too much Delta 8 can cause the same scary feeling that too much Delta 9-THC can cause. While I do think that this feeling occurs because that was how God INTENTIONALLY DESIGNED it to affect people once their dose reached the upper limits that God wanted people to consume (as a built in abuse deterrent), it can be frightening nonetheless. Taking too high of a dose of Delta 8 or regular ol’ Delta 9-THC can be physically and psychologically uncomfortable, and being in such a state also poses spiritual danger to you. When you consume too much and you enter this confusing, scary space, it is easier for demons to mess with you and put evil/fraudulent thoughts in your head.
Because of this, I advise EVERYONE who wishes to use Delta 8 to be watchful and mindful that you don’t overdo it and take an amount that leaves you open to a panic attack and demonic control. This is the level/dose where you are no longer in control of the drug but it controls you. This is NOT a good place to be in, but with the exception of Alcohol and other GABAergic drugs like Xanax, Valium and Barbiturates (most commonly “Aceta-Butal-Caf”) which make you feel calm and fearless even in high doses, with most other categories of drugs (especially cannabinoids), the dose at which the drug controls you is unpleasant and produces a frightening sensation like you are going crazy, feel like you are going to die or feel very sick. Almost every type of psychoactive plant medicine causes this to happen at higher doses, which are beyond the dosage level that God intended for people to take.
While I believe that God created them that way on purpose to try to scare people away from over-consumption of psychoactive plants, I still recognize that it is an uncomfortable experience that can open you to racing heart beat, high blood pressure, temporary psychosis and the possibility of being controlled or possessed by a demon. That is why I’m placing such a big emphasis on controlling your dosage when taking Delta 8, and in fact I believe that God specifically told me to tell people this when I shared info about Delta 8. By following my guidelines, you can enjoy the medicinal benefits and slight “pleasure value” of Delta 8-THC without overdoing it and experiencing the negative effects that can come from excessive use.
So, in closing, I want to give an example of how people should go about starting off with Delta 8 and how to properly control their dosage.
For use in Vape pens:
If you have NO tolerance to regular THC, then when turning on a vape pen with a distillate cartridge attached, after turning it on, hold down the vape button for 1 second and inhale at the same time that you are holding down the button. Take a quick little puff/hit and hold it in your lungs for about 5 seconds, then exhale. Now, turn the pen off and sit and wait. You should feel the effects begin immediately though mild at first, and within about 15 or 20 minutes you’ll have reached the highest strength of effects, and then it will gradually begin to fade and transition into that OH SO COMFY warm and fuzzy, soft feeling all over your body that feels similar to codeine. The remaining effects should last for about 1 to 1.5 hours. If you take a typical dose of CBD oil or vape a small dose of full spectrum CBD concentrate/hemp flower prior to vaping the Delta 8, it will feel virtually identical to regular marijuana except there will be little or none of the negative psychological effects that traditional THC can cause.
A short 1 second puff of Delta 8 from a concentrate vape cartridge will be around 0.7 to 1 milligram of Delta 8-THC depending on the purity of the distillate that is in your cartridge. Most Delta 8 concentrates on the market today range from 65% to 95% Delta 8-THC, with the remaining percentage of compounds being other cannabinoids and compounds that were extracted from the plant, and possibly terpenes, which are like the essential oil of the plant. However, the more yellow or orange the color of the extract is inside the vape cartridge, the more “full spectrum” the effect will be. My 92% Delta 8 distillate from my cartridge actually feels “incomplete” and less effective than if I consume it along side some CBD extract or hemp flower.
For use in edible Oil or other oral form:
The oil that I use is from a company called Loud House Hemp, and it is 700mg of Delta 8-THC in 30 mL of MCT oil (which is fractionated coconut or palm oil that stays liquid at room temperature. After calculations, this oil turns out to be 777 micrograms of Delta 8 per drop from its included bottle dropper. 777 micrograms equals 0.777 milligrams. If you swallow this oil immediately, the effect is much more subtle and takes a few hours to kick in, and even for someone with NO tolerance to regular THC, they probably wouldn’t notice anything from 1 drop consumed orally. They’d have to take at least 2 or 3 drops to feel something from swallowing them. If you drip the drops onto your tongue and just sit there and close your mouth and hold it on your tongue for a minute, it will absorb much faster and easier.
For someone brand new to trying Delta 8, if you have no tolerance to regular THC (ie you don’t use marijuana on a regular basis), then start with 1 drop on your tongue. You can just stick your tongue out while holding the dropper in front of you and watch yourself drip one drop onto the front part of your tongue, then you can cap up the bottle and hold your tongue and mouth still for a minute for the drop to absorb. You should feel effects from this almost immediately and it should fully kick in within 15-20 minutes. Try this, and see how you feel. If you feel like that dose was too low, wait until the next day and try 2 drops on your tongue, using the same method I just described. Gradually increase the dose from there as needed, going up by 1 drop at a time until you find the dose that’s best for your needs.
For topical use:
You will need Delta 8 dissolved in some liquid for this to work, so since most versions available are oral oil forms like what I described above from Loud House Hemp, we’re going to use that in this example.
So, you can rub the Delta-8 oil anywhere on your skin, but rubbing it over your wrist or the “IV” location in your inner elbow is the best place to apply it since the Delta 8 will absorb into your blood stream much faster if it’s rubbed in over top of some visible veins.
I made some Delta 8 dissolved in 91% Isopropyl alcohol, and it kicks in just as fast as inhaling it, but most of my readers won’t have the skill or knowledge or desire to make this kind of thing safely and correctly at home, so I won’t bother telling how I made it, at least for now in this article.
The Delta 8 oil that we are using in this example is dissolved in MCT oil, and while it absorbs slower when applied topically, it still kicks in pretty quickly… within a minute or two. For this method, just drip 1 drop onto your wrist or other venous area of your body and rub it in until the greasiness feeling is pretty much gone, or it is absorbed into the skin as much as it will in that moment. Then just wait for the effects, and that’s it. Same as with trying the oil by mouth, if 1 drop is not sufficient to give you the effect you desire, wait until the next day and try 2 drops and see how that feels. Keep going, gradually increasing your dose by 1 drop of Delta-8 oil until you find the dose that works best for you.
For other inhalation methods:
Ok so for this one, I REALLY don’t recommend that any of my readers do this category unless or until they have a relatively high tolerance to Delta 8 already (from oral, topical or vape pen use), or if you are someone who already has a tolerance to traditional THC like that found in marijuana or dronabinol capsules. I say this because after a few days of receiving and using the Delta 8 vape cartridge, I decided to extract the Delta 8 from the cartridge, and when I took the mouthpiece off of the cartridge, it had a little bit of Delta 8 distillate stuck to the bottom of it. I used a paperclip to scoop off just a TINY, TINY amount of distillate, a SUPER tiny amount, and I used it in an e-nail (an electronically heated dab rig) which is used for vaporizing cannabis concentrates. This TINY little speck of Delta 8 distillate used in my e-nail dab rig got me BLASTED to a level I did not want to be at and was not comfortable at all! I managed to not panic and I went in the kitchen to eat and drink and watch TV and that helped keep me sane until the effects weakened to a comfortable level. I realized at that point that if I wanted to vaporize Delta 8 I had to do so in a vape pen or dilute the pure distillate into some CBD extract or hemp flower at a carefully measured dose so that I would have just the right amount each time I used my vaporizer or e-nail, and not have a repeat of what occurred with my first Delta 8 dab attempt.
So, if you already consume regular THC on a frequent basis (for medicinal or recreational purposes) then Delta 8 may not be for you, or it may, depending on how it makes you feel compared to regular Delta 9-THC and what your medicinal needs are. If you meet this qualification, or if you have reached the point where you need over 10 puffs from a Delta 8 distillate concentrate vape pen to get your proper medicinal level of effects (where you can function properly and aren’t out of your mind), then you can go ahead and try dabbing Delta 8 but do so with EXTREME CAUTION regarding your dosage. Use a sewing needle or a lengthened out paperclip to measure your Delta-8 extract out of the container and into the dab rig, e-nail or nectar collector, and start with the tiniest amount you can scoop up and fit on the end of the needle or paperclip. After you’ve dabbed that, wait at least one and a half hours before trying a larger sized dose if the first was insufficient, but even then be VERY gradual and careful with how much you increase the size of your dab serving.
Alright, so that’s all I’ve got for now. I’m not sure when or if I’ll sell any Delta 8 or other types of hemp products, but I’ll certainly keep using them for my own medical needs and teaching other people how to do the same in as safe and cautious and mature of a manner as possible. As of right now, I don’t have any financial connection to the companies that I mentioned whose Delta 8 products I bought, but if I ever become an affiliate for them or for anyone else, I will let you know that I may receive a commission payment if people purchase such products through links that I would provide in the article. However, as of right now, I have no such arrangement and at this point in time I will not benefit financially if you make purchases from the companies I mentioned in this article.
Here are their websites if you want to check them out for yourself:
This one links to a page with various Delta 8 products:
I have purchased some more Delta 8 products from another manufacturer and I am still waiting on them to arrive and try them out. Once I try them out I will update this article to include a link to purchase through them IF they are of good enough quality to get my stamp of approval.
If you place an order with any of the companies I’ve mentioned in this article, if there is any problem with shipping delays or payment processing, I apologize but you will have to take the issue up with them if that occurs. I cannot control when such things happen, but the two companies I listed above have treated me well and courteous at all times.
I hope this has been an informative article for you guys! I hope you’ve learned a lot of helpful info, and I can’t wait to hear back from you if you decide to give Delta 8 a try. Please reach out to me and let me know what you think, along with any questions you may have as it pertains to hemp, cannabinoid science, health questions in general, etc. Leave a comment below, send me a message through the email contact box on my Contact page, or connect with me on Facebook or Youtube. Also, please Like, Subscribe and share this content so that more people can learn the valuable information that you just learned today.
Take care, and have a Blessed Day!
– Joshua Porch, Founder and CEO of Bio Hacking Academy
Hi everyone, I’m Joshua Porch, and welcome to this latest teaching from Bio Hacking Academy.
In this lesson, I’m going to be teaching some revolutionary things that most people have no clue about, even though these things have a serious impact on your quality of life, whether you are a man or a woman.
Most people don’t realize it, but Estrogen (in it’s couple of forms) and the various Estrogen receptors have a LOT to do with pain sensitivity in men and women alike, though in slightly different ways in each sex. Estrogen and anything that activates their receptors blocks the mu opioid receptors. That’s the type of receptor that vicodin, morphine and other commonly abused (and effective) opioid pain killers activate. There are other types of opioid receptors, but they don’t produce euphoria like the Mu receptor does.
Because Estrogen blocks the Mu receptor, it can increase pain in people who already have some sort of injury, chronic pain condition, or who are already taking opioids on a regular basis for any reason. Granted, Estrogen does have its place because it also increases Mu opioid receptor density at the same time as blocking it (that’s how it works with almost all types of receptors in the human body). Still, any kind of compound that increases Estrogen and lowers testosterone can worsen pain in both men and women, but especially men.
Women’s bodies have adapted to the high level of Estrogen and increases in it’s activity have less of an effect on women’s pain perception as it does in men.
How do I know this?
Well, the discovery initially came by accident. I had noticed that certain herbs or medicines in the past had worsened my pain, and some had made it better, but aside from actual opiates, I never understood the full reason why some things increased my pain and others helped it. What I later learned is that most of the herbs and medicines I’d tried that increased my pain happened to also increase Estrogen levels by raising aromatase enzyme levels, OR they mimicked Estrogen in some way and were in some way a partial or full agonist at one of the Estrogen receptors.
I learned that THC was one of these, but it turned out that THC had a U-shaped curve regarding pain relief, that low and high doses improved my pain but medium doses made my pain worse. I later learned that it had to do with re-sensitization and up-regulation of the mu-opioid receptors. You see, if I had Kratom in my system, a very low dose of THC would make the Kratom more effective because that small dose of a Mu-receptor antagonist (THC) made them more sensitive to the Kratom that was already attached to them.
Then, whether I was taking Kratom or not at the time, medium doses of THC would act as a Mu-opioid receptor antagonist (blocker) at pretty solid strength, and it would make my pain worse, a lot worse. It would make the muscles tense up and feel constantly electrocuted.
Finally, high doses of THC would do something totally different. They would block the Mu-opioid receptors so much that they would begin to rapidly multiply and increase in number to try to make up for it. At the same time, the increased cortisol and GABA receptor blocking activity of the THC would cause my body to release endorphins which would then attach themselves to the newly created Mu-opioid receptors and then would relieve my back pain. However, at this point, the THC psychoactive effects would be so strong that it was scary and uncomfortable, not fun at all. It was so bad that most of the time I couldn’t stand feeling that way and decided that THC must just not be a viable pain relief option for me anymore since the only dose that fully relieved my pain made me lose my sanity and feel like I was dying.
I didn’t know this at the time, but THC stimulates one of the Estrogen receptors, so in a sense it mimics Estrogen. At the same time, THC also increases cortisol which increases the aromatase enzyme which then causes your body to make more Estrogen. A double whammy! At the time that I was taking prescription THC pills (legally prescribed to me), I knew that sometimes they helped my pain and sometimes they didn’t but I didn’t understand why at the time.
Probably a year or more later after I had finally stopped taking THC pills (and switched to Kratom instead), I tried something else, which led me to another accidental discovery that has helped me out a lot since then. I found this pheromone infused soap and it was pretty cheap compared to other pheromone products. It was about $10. I honestly just tried it to see what all the fuss was about. I had no idea if it was going to affect random women’s attraction to me or not, but I figured it’d be a cheap experiment to see if it’d have any merit. That’s when I learned something I never knew before about pheromones.
It turns out that they are actually other male hormones besides Testosterone, specifically they are Testosterone metabolites. They have a REAL, very noticeable affect on men and women when applied physically to their bodies. When I tried the soap for the first time (“Bond” by Tactical Soap Company), I didn’t feel anything until a few minutes after my first shower. Then I felt almost as if I had been injected a testosterone shot! I felt Alpha as heck! I felt like the top dog, like what I imagine it feels like to be the richest, most attractive jock in high school, who had 12 girls hanging on his arm everywhere he goes.
I learned a few important things experimenting with this Pheromone infused soap. First, it made me feel like I had much higher testosterone levels than I actually had. I knew that the Kratom was lowering my testosterone, but I had to have it to control my back pain. Nothing else really worked to relieve my pain. Back when I had been taking testosterone replacement therapy shots, I felt a lot better during the days when my testosterone was high (the shots caused high and low days). I had problems with the doctors and insurance company, so that’s why I stopped taking it. However, when I was on Testosterone, I felt a lot better. My pain was lessened and I had much more energy and physical stamina, and a spectacular mood that mimicked the feeling of being a successful CEO or celebrity. The pheromone soap mimicked the feeling very closely, about 90% similarity. I found that taking Rhodiola capsules with it amplified the awesome feelings from it even more!
Second, I learned something that was not so fun. See, the pheromones only last a few hours before they begin to wear off, and when they wear off, I began to feel depressed, moody with a “lump in my throat” kind of feeling, I’d feel edgy, and my pain would increase to equal or greater levels than it was before using the pheromone soap. There is always a crash with any supplement, medicine or recreational drug. Hormones are no exception.
At first, I didn’t know why this was happening, this sudden worsening… then something hit me. Pheromones were ANDROGENS, that is, male hormones, and they stimulated the androgen receptors just like Testosterone. So when they wore off, it had the same effect as taking their opposite compound (Estrogen). Androgen rebound mimics or increases Estrogen. Estrogen rebound mimics or increases Androgens. That’s how it works in men and women alike.
Once I had this realization, all the pieces of the puzzle started to fit together to form a big picture. Everything that mimicked Estrogen or caused it’s levels to increase caused all of the same symptoms of having low Testosterone! Everything that lowered Estrogen or raised/mimicked an Androgen (like Testosterone) made me feel better in every way (for the most part).
One problem I did notice when I was receiving the Testosterone shots was that they would initially cause a lightheaded feeling along with shortness of breath. I didn’t know why this occurred, but it only happened when the levels of Testosterone suddenly got above a certain level… I guess above what is a physiologically normal level. This is what would happen when first getting my Testosterone shot, and when I later tried some experimental Testosterone boosters that were really strong, certain doses of them had the same effect on me even though they weren’t injections of actual Testosterone.
It wasn’t long before I learned why this happened. Cortisol, while it does break down muscle tissue, is also important and vital to proper breathing. Testosterone lowers cortisol, and that sudden lowering of cortisol along with other factors related to how Testosterone affects blood oxygen levels is what is responsible for the lightheadedness that comes right after the injection. However, this also causes a sudden surge of muscle building and pulling sugar out of the blood and drawing it into the muscles to be stored as glycogen.
Then, I came to another realization. If Estrogen blocks the Mu-opioid receptor, and if Estrogen and Testosterone have opposite functions, then Testosterone must activate the Mu-opioid receptor. Sure, the shots didn’t completely get rid of my back pain in absence of Kratom, but they boosted the effect of the Kratom in regards to pain relief and euphoria. Thus, I came to realize that Testosterone did function partially like a traditional opiate, but it was weaker than Kratom or Vicodin (Hydrocodone). That made everything make a lot more sense in my mind.
I’m going to wrap this up now.
I found that continual use of Testosterone-boosting and Estrogen-lowering supplements, along with gradually increasing exercise, along side my Kratom, gave me the best balance of pain relief and improvement of my fitness. I’m still in the process, still in the journey of improving my body, as my musculature, fat levels and overall physical stamina have gone up and down over the years depending on my income and life responsibilities at the time. I decided that enough was enough though. I was determined to do whatever it took to keep a constant (even if slight) improvement going in my fitness and aesthetics, no matter what is going on in my life. While I still have a ways to go, I believe that I’ve finally found the right balance of cheap, easily available herbs (aside from the Kratom) to allow me to overcome health and fitness challenges that have plagued me for most of my life.
I believe that by taking note of the insights and strategies I mentioned in this article/post, you too can improve your fitness, pain levels and many other things by manipulating the Estrogen system in your body. It IS important to give your body some periods of time to recover, however, to let Estrogen levels return to normal or even elevate for a short time. Estrogen does have health benefits, and it can also re-sensitize the Androgen receptors as well as the Mu-opioid receptors, leading to your body being more sensitive to Testosterone and Endorphins (or other opioids) and gaining whatever benefits may come from those compounds (whenever they are needed).
I suggest (as my personal, non-medically-licensed opinion) that men and women seeking improvement in their pain levels and fitness take Testosterone-boosting and Estrogen-lowering supplements either on a 3-day-on then 1-day-off schedule, or a 3-week-on then 1-week-off schedule. Women should take half of the recommended dose for men. If women begin to develop masculinization or other severe problems (which is unlikely with OTC test boosters), either stop the supplementation entirely or cut it down to 1-week-on then 1-week-off and repeat this cycle. If problematic side effects for women or men get bad enough, stop use all together.
Through Bio Hacking Academy, I teach people how to alter their physiology (how their body works inside) in order to help people reach their goals, but every method I teach has the possibility of causing unwanted side effects. No change in supplements, medicines or food is completely side effect free. It is up to you, the consumer, to decide if the side effects of a given treatment or method are worth the benefit. I simply teach people how different important functions in the body work, and how to alter them as closely as possible to your liking… but that is it. It is up to you to do the work, and use common sense and judgment to decide if something that I or anyone else is recommending you do to your body is right for you.
I hope this has been an impactful and insightful message, and I look forward to seeing and hearing from you how these tips have helped improve your fitness, health and overall quality of life!
I’m sure you know me by now, but in case you just stumbled upon this, my name is Joshua Porch, and I’m the founder of Bio Hacking Academy. I’ve made it my mission to understand all that I possibly can about the human body so I can help myself and as many people as possible to take control of their health, not just to help in the fight against disease and ailments that are so common to the human race, but to help people fine tune their bodies to supercharge them into the highest performers possible!
In past videos I’ve covered Serotonin in depth, I’ve covered a bit about Dopamine, and I’ve shared lots of info regarding CBD. One neurotransmitter that is not discussed often enough however is Norepinephrine, along with it’s metabolite Epinephrine. These neurotransmitters play a large role in many of the trickier aspects of physiology and psychology that the majority of mankind do not understand too well. Norepinephrine and Epinephrine can be your friends and your foes, depending on the circumstances. There are even some occasions where they can serve as both at the same time. I’ll explain how in just a little bit.
You see, one aspect of the human experience that has always remained elusive to me is why people act the way they do when they get angry, why people lose control under certain conditions, and why some people have a better stress tolerance than others… that is to say, why some people take so much longer to get angry than others even when they are in the exact same situation.
The answer to this is complex, because there are a multitude of factors that affect people’s behaviors and responses to situations. Someone who’s had a bad day already filled with 15 different stressful events prior to the current one will be a lot more likely to fly off the handle than someone who’s had a great day so far and just now experienced their first stressful event of the day. But why does it work that way? Why does the body become less tolerant to stress as the day goes on (usually)?
Norepinephrine and Epinephrine play a key role in this!
You see, when a stressful event happens, the body releases Cortisol… that’s why it’s called the “stress hormone.” Truly, Cortisol is not the stress hormone but it’s the main one. Cortisol causes Dopamine and Serotonin to be released into the blood stream and throughout the brain. However, the Serotonin is quickly depleted, and the Dopamine is converted into Norepinephrine. While Dopamine provides the initial motivation for focusing on the problem and trying to figure out how to solve it, once it gets broken down into Norepinephrine, the body shifts more to a state of “fight or flight.”
When this happens, the Norepinephrine makes the person into a tough, grouchy productivity machine. The Norepinephrine makes a person become aggressive and ready to fight, and it’s designed to make the person act in such a way as to hopefully intimidate any would be troubling people or animals into being afraid and not messing with them. When the problem that’s occurring has to do with a vehicle, object or some other thing where there isn’t an interpersonal threat, then the effect of the Norepinephrine becomes more of a hindrance.
The Norepinephrine is then converted to Epinephrine, which raises blood pressure even more and puts a person in a bit of a frenzied state. It is a large contributing factor that makes people get road rage, “slow computer rage”, “video game rage” etc. It’s one of the main contributors to people’s veins bulging and their face turning red when some problem is really aggravating and it won’t go away or seems unsolvable/unfixable.
So, the reason that people who’ve been through 15 stressful events already in a given day lose their temper easier than someone who has only experienced zero, or one, or two stressful events thus far in the day is because every time a stressful event happens, the body builds up levels of Norepinephrine and Epinephrine which take time to go down. In addition, the body becomes depleted in Serotonin, Dopamine, GABA and other happiness/pleasure related compounds. When many stressful things happen over and over, and close together, the body builds up higher and higher levels of Norepinephrine, Epinephrine and Cortisol levels while being depleted of the “happy” chemicals. This creates a perfect storm that our society has not yet reached the state of learning how to deal with properly.
Unfortunately, our bodies don’t recognize that the flood of stress hormones and neurotransmitters (which includes Cortisol, Glutamate, Dihydrotestosterone, Estrogen and more) is harmful if the perceived threat is an inanimate object, electronic device, machine, or a line of cars in front of us where no matter how mad we get, we can’t make the people in front of us move when we want them to. The excess Cortisol and Glutamate that happens in the brain during extreme or prolonged stress disrupts the Pre Frontal Cortex where critical thinking, logical reasoning and emotional stabilization occur.
So, what most people don’t realize is that when someone loses their temper and says something they later regretted and they swear that they didn’t mean to say it, they usually aren’t making up an excuse, they’re giving a 100% honest answer about something that their body chemistry made them do that was totally out of their control… and they had no way of foreseeing it or stopping it from happening. It is this lack of proper understanding of how the body works that causes so much unnecessary dysfunction and quarreling within families, among law enforcement and judicial officials, paramedics, psychiatrists, etc.
To further complicate the issue, most people in the medical and psychiatric community don’t know how to treat or prevent anger appropriately. It happens to everyone, but this is in regard to people who get angry especially easily or more frequently than the average person. Certainly, their individual circumstances have a role to play in how often people get upset and why, but even then, if the right chemicals could be changed in the right way at the right time, people wouldn’t even get angry if someone spit a bunch of snot on their face or punched them in the nose, etc etc. It all comes down to keeping the stress hormones and neurotransmitters from getting too elevated, but that is where the problem lies.
You see, in order to prevent people from ever getting angry for any reason, the medical industry would have to figure out a way to create a medicine or medical device that was capable of preventing the anger inducing neurotransmitters and hormones from becoming elevated during a time of stress while at the same time not making those endogenous chemicals be too low during normal times of day that are not stressful. The kind of technology that would be required to accomplish this task simply doesn’t exist right now and quite possibly may never exist.
It is possible in theory that something which had the ability to be an allosteric modulator of each of the receptor cites for all of the neurotransmitters and hormones in question could accomplish this goal, but I don’t think it would ever be possible to create one drug which could have that effect on that many of the correct receptors simultaneously. If something like that was to be accomplished, it would have to be through a medical device.
The only possible conceivable solution I can think of would involve something similar to an insulin pump, some sort of implant or box which attaches to the body and has an IV or IM insertion point where a port would remain in place for the machine to inject the right drugs at the right time. With such a machine, it would have to constantly monitor many different levels of hormones, neurotransmitters and electrical activity within the body 24/7.
The machine would have to detect when stressful events were beginning to occur and continue monitoring the body throughout the stressful event, and the machine would have to inject the right kind of drugs at the right time in the right amount at the right diffusion rate in order to keep the body’s stress response at neutral, or in essence, eliminate the fight or flight response. This could of course pose several dangers if it was ever possible and real.
First of all, the biggest danger would be if someone was about to be run over by a vehicle or was being chased by an animal, this lack of fight or flight response could result in the person not getting out of harm’s way fast enough. Secondly, if someone was confronted by another person who wished to physically harm them, the lack of stress compounds would make the victim unable to fight at a fair level, which would obviously increase their chances of being hurt or killed.
Finally, lack of stress compound elevation could make someone remain docile and non-confrontational towards someone who was trying to do something seriously harmful to that person on an emotional, financial or social level. There are just some times where sitting by and refusing to stand up against someone who is ruining your life by their ignorant, irresponsible or evil behavior might as well be a suicide sentence upon yourself.
While we ought to be as nice as possible for as long as possible, I believe that God Himself would not even want someone to allow their lives to be destroyed by someone who was trying to take control in ways which they don’t have the right, and who don’t really know what’s best for someone else’s life, even if they really think they know best. Such people sometimes need to be told off in order to keep your boundaries respected and your life as trouble free as possible.
Of course, technically cursing is a sin but I also believe that because God understands that chemical/medical factors can make someone lose control of their words from time to time, I believe that He takes that into consideration, especially if the person later regrets or apologizes for what they said. Even if you feel the need to apologize to someone or try to bury the hatchet, it may be best to keep your distance and lessen the frequency of your interaction with that person if you know that communication with them will often lead to worsening of your quality of life and undue stress that could otherwise be avoided… this even applies to family as unfortunate as it may be.
In closing, “Norepinephrine and Epinephrine play a key role in the management of stressful situations, but they also have benefits such as helping provide increased focus, motivation, physical energy, muscular performance enhancement, and more. While these compounds may sometimes bring about consequences that we wish we could avoid, without them we would be sitting ducks with no energy, virility, sense of self preservation or drive to protect our loved ones.
I hope you’ve found this article helpful and informative, and I hope that it clears away some of the mystery surrounding stress and anger. Please stay tuned, and until next time, take care!
As you may have read already in my last blog post, I have an extensive history with Chronic Pain, stemming back to around age 10 or 11. I have experienced multiple types of pain over the years, some occasional and some almost always constant. Over the years, I did a lot of studying scientific literature, reading anecdotal experiences of others with Chronic Pain, and testing lots of different things on myself (from a medicine/supplement standpoint as well as many non-drug therapies).
Over the years, through trial and error and through advancements in my scientific discoveries, I found that there are many different sources of pain (speaking from a bio-chemical level). I will do a brief overview of each, and how and why each thing works that way. This guide is going to be a bit lengthy, but I’ve tried to make this as easy to understand as possible for laymen, as there is a lot to cover, but this is not going to be a comprehensive teaching on the types of pain I will be telling you about below, but rather, an overview of each.
First of all, I’ll just list several different potential causes of pain, and then I’ll explain a little bit about how each of them work. While these statements may be supported by scientific literature that is available to the general public, these are merely my opinions based upon my research and personal experiences with Chronic Pain and searching for the root cause. I am not a licensed medical practitioner and none of what I write about should be considered to be official, government sanctioned medical advice. Please discuss what you learn below with a doctor or pharmacist prior to taking action upon anything you learn here.
Causes of pain can be from:
Inadequate levels of GABA
Inadequate levels of GABA-like endogenous compounds
Something causing the GABA receptors to be blocked (AKA antagonized) or highly desensitized
High levels of Cortisol
High levels of Acetylcholine
Other compounds causing excitotoxicity
Diabetes or abnormally high levels of Human Growth Hormone
Activation of the Vanilloid Receptors
Nerve Damage caused by physical damage or chemical means
Opioid receptor antagonists, opioid receptor desensitivity, or inadequate endorphin levels
There are more causes, but this is all that I have sufficient knowledge of to be able to comment on. Also, some of these areas I’m more educated than others, but I still know at least the basics in each of the bullet points above.
The first 3 bullet points are all kind of grouped together, so I’m going to address them all at the same time. First, I’m going to explain how the GABA system works so that you’ll understand it better in regards to pain signaling and control.
GABA slows down the rate at which nerves fire electrical impulses and this includes the speed at which different receptors pulse out and receive neurotransmitters across the synapse (the synapse is the space between the “sending” receptor and the “receiving” receptor). Don’t worry, if this seems a little bit over your head, please check out the following videos for a better explanation of how receptors work, here and here.
Video 2 – If the video doesn’t start at 0:00, please rewind it to the beginning… Youtube is being DUMB!
GABA antagonists on the other hand, increase the speed at which nerve impulses fire. For some reason that I have yet to fully understand, in many cases it turns out that increased speed of electrical impulses through nerves causes both nerve pain and muscle tension (tight, contracted feeling).
The reasons I mentioned above can greatly play a role in pain because GABA slows down everything and causes the muscles to relax and move more slowly, while GABA-antagonism can cause tight, tense muscles, electrical sensations and that “pins and needles” prickly nerve sensation. Higher GABA activity will tend to lower anxiety but also lower energy and alertness, while low GABA activity (or having the receptor blocked) can cause anxiety but also increase energy and alertness up to a certain point. Once GABA receptor antagonism goes too high however, the person experiencing it just feels fried, burnt out, terrified, and very confused, with common examples being overdoses of THC, synthetic cannabinoids, or high doses of alpha-thujone (the main psychoactive component wormwood, some types of absinthe, etc).
Strangely enough however, thujone has been shown to have pain relieving properties even though it blocks the GABA receptor. However, it is a pretty finicky compound best used for occasional recreation in small quantities rather than a regular part of a pain killing regimen.
Ok, moving on, we next have Cortisol. This compound is the primary stress hormone in the body, and is a double edged sword. It is required in certain amounts to deal with stress properly, as well as to have energy and stay happy throughout the day. However, Cortisol causes a release of neurotransmitters which then depletes them after a little while. Prolonged Cortisol elevation will cause an initial “high” followed by a prolonged “low”! The initial boost of Dopamine, Norepinephrine, Epinephrine and Serotonin that comes from Cortisol can make someone alert and ready to tackle challenges, but once these neurotransmitters get used up, it takes a while for your body to create more. It is in the low state that people feel drained, weak and often sore and achy. So while high cortisol levels may actually make someone pain free temporarily, they’ll be feeling wretched when the boost wears off.
To go along with Cortisol, the next thing to mention that can cause pain (or muscle fatigue) is Acetylcholine. Acetylcholine is a stimulant in low doses, but a relaxant in high doses. However, it’s relaxant properties cause muscle weakness, rather than a pleasant relaxation. Acetylcholine and Cortisol go hand in hand. Acetylcholine causes Cortisol to be released, and what happens with large doses of Acetylcholine is that the Cortisol gets released in a burst, then quickly depleted, and it is in this depletion state that the muscles become weak and often sore. It isn’t just Cortisol depletion however. You see, like I said earlier, Cortisol releases Dopamine, Serotonin and Norepinephrine/Epinephrine, so when those compounds get used up and are depleted in your system, you are left with a body that’s low on almost everything except Acetylcholine. This leads to feeling burned out.
Beyond Cortisol and Acetylcholine, there are other things which can cause pain which are called “excitotoxins”. These are compounds which cause an increase of activity at the cellular level to such a great extent that it essentially “fries” the cell and causes it to die or become severely damaged from a sudden surge of overactivity. The biggest example of this includes the neurotransmitters Glutamate and N-Methyl-D-Aspertate (which activate the NMDA receptor). There are also many natural and man-made chemicals which mimic the effect of Glutamate or NMDA, and while they do have their place in proper biological functioning, these compounds can cause a lot of problems if levels get too high, one of them being pain.
You see, in the human body, there are many different systems linked together, and changes made to one system cause a cascade effect that affects other neurotransmitter or hormone systems in the body. For example, GABA (or GABA mimicking compounds) lower or block activity at the NMDA receptor, which often times helps treat pain and protect against nerve damage, resulting in an inhibitory effect (like alcohol or xanax). On the other hand, things which lower GABA or block the GABA receptor cause an increase of activity at the NMDA receptor, resulting in an excitatory effect (like caffeine, cocaine or amphetamines). The nerve damage that can occur from over activation of the NMDA receptors can result in different types of pain throughout the body.
Next, we’re going to cover the pain that comes from Diabetes, and also a surprising culprit… Human Growth Hormone. So, you may have heard of something called “Diabetic Neuropathy” but unless you have it personally or someone close to you does, you probably don’t understand what it’s like too well. There’s one thing that both Diabetes and Human Growth Hormone have in common that is linked to nerve pain, and that is high blood sugar. While you may know that Diabetes is when your body has too high of blood sugar and it can’t properly lower it to a normal level via the insulin response like it’s supposed to, what may come as a surprise to many people however, is that Human Growth Hormone causes an increase of blood sugar levels as well. This is strange, since HGH is a fat burning compound that’s also supposed to help muscle growth and recovery. It just works in a different way than most people expect. I’m not going to get into the specifics in this post about how that works, but understand that high blood sugar, no matter the reason, can cause nerve pain which often feels like pins, needles and sharp, burning electricity in different areas of the body, and it often times doesn’t go away, or takes a long time to go away without medical intervention.
I know that some of you guys might be thinking that this guide or post is getting pretty long, but I aim to help as many people as possible through this. I assure you though, we are starting to wrap things up now. Just a few more bullet points, and we’ll be done.
Now of course, this guide wouldn’t be complete without discussion of Physical Injuries as a cause of pain. This can range from smashing your finger with a hammer, to a needle stick, to scoliosis, dislocation, spinal disc damage or broken bones. I know a thing or two about this, because not only have I had many accidents as a kid while playing around, but I just recently within the last few months found out that I developed scoliosis as a child around the age of 10 or 11 and over the years I also somehow managed to get half of the bones in my spine misaligned, twisted either to the right or the left of where they should be. This misalignment caused pinching of the nerves in my spinal cord, and the curvature of my spine (the scoliosis) caused tension in various muscles in my back because they were/are always twisted due to the spine not being completely normal.
Obviously, it’s good and vital for our survival to feel pain when we receive a physical injury because it tells us what activities we need to avoid and how much rest we need in order for it to heal properly… at least, that’s how our bodies are supposed to work. When a physical injury is unable to be healed for one reason or another, and the pain persists when there is nothing that can be done to fix the injury short of divine intervention miracle healing from God, then the pain signaling becomes a bad thing that makes us suffer for no good reason, and that’s usually where pain medication and/or nerve blocks come into play. However, I am extremely against nerve blocks unless there’s absolutely no other possible choice, because although it is very low, there is a risk of permanent paralysis and/or worsening of pain beyond what it was originally, if the practitioner accidentally hits the wrong spot while giving the injection into your back. Same thing with back surgery… the risk of things getting worse… I just can’t do it. I’m suffering enough as it is, but a select few types of drugs are currently working pretty well for my pain, and the side effects they present are much less severe than paralysis or increase of pain.
The next thing we’ll be covering are the Vanilloid Receptors. Despite it’s name making it sound like Vanilla, the Vanilloid receptors are actually best known for being receptors which respond to heat and noxious stimuli, like Capsaicin (the hot ingredient in hot peppers), burns from a flame, hot light bulb, hot water, etc. They are also involved in the sensation of cold. The main thing is though, activation of the Vanilloid Receptors (particularly TRPV1) causes pain which feels like heat, burning, and inflammation, while ingredients which block the TRPV1 receptor lower pain and can also bring a feeling of cool. Examples of TRPV1 blockers include CBD, other Cannabinoids, and the herb Yerba Santa, though more TRPV1 antagonists can be found through more deep research on the internet or biological publications. This is particularly why CBD can help relieve pain but at the same time, larger doses can make people feel cold, because the heat sensing TRPV1 receptor is being blocked in that case. I can say though that when you are in a lot of pain, feeling cold and having to lie under a blanket for a while is a welcome temporary side effect in order to get rid of the pain (unless it’s in the middle of the day and you’ve got urgent errands, house hold or parental duties to take care of… then it’s miserable!)
Ok, we’ve only got two more bullet points and then I’ll be closing.
Next, we’re going to cover nerve damage from chemical or physical harm. This should sound pretty self explanatory, but I’ll still give examples of each. Nerve damage from a physical harm would be like if you dropped a heavy object on your foot and even after you got it off, you have tingling in the foot and leg even after the initial injury and pain has gone. Even if the tingling isn’t painful, it is still very annoying when it won’t go away, but usually the tingling is painful indeed.
An example of a chemical harm that can cause nerve damage is vasoconstrictors… basically, drugs that constrict the blood vessels and raise blood pressure. If the blood vessels get too tightly constricted, blood flow to certain areas of the body get completely cut off and the cells in that area begin to die off from lack of oxygen. When this happens around nerves, you have nerve cell death which can lead to loss of feeling in certain part of your body, or it can be neuropathy… which is, that tingling, pins and needles feeling. An example of a kind of compound that can do this is the Ergot fungus and many of it’s derivatives, of which LSD is one (though LSD is physically very safe regarding vasoconstriction). Eating LSA containing seeds in high doses, eating ergot fungus, etc can cause vasoconstriction so severe that a part or parts of your body will either fall off due to gangrene or it will loose feeling altogether for sometimes several months before enough regeneration can occur in the area to restore feeling to what it originally was. Low to moderate doses of LSA containing seeds do not pose this danger however. That being said, consumption of LSA containing seeds is illegal in some countries including the United States, so take what I just told you as for informational/educational purposes only.
The final bullet point now has to do with opiates, or more specifically, inadequate endorphin levels or having opioid receptors blocked by an antagonist (such as naltrexone and naloxone). It is thought that Borderline Personality Disorder is caused by people who have too little endorphins in their bodies. While it is not a government approved treatment, many people with Borderline Personality Disorder have found that self medicating with opioids or endorphin-boosting medicines makes their BPD symptoms virtually vanish, as long as the drug is in their system in sufficient quantities that is. One of the things that people with BPD often experience is an increased level of pain on a day to day basis, and often times chronic pain in at least one particular part of their body, though sometimes it can move around and go up and down in intensity throughout the day.
You have to look at it this way… opiates and opioids relieve pain, endorphins (which are your body’s own natural form of opiate) also relieve pain… so if increasing them can improve pain, it only makes sense that lowering them or blocking their receptors will increase pain. This is true most of the time. One great example of this is coffee. Coffee contains a small amount of opioid receptor antagonists. When you have one or two cups of coffee, the amount of antagonists getting into your system is so small that it either doesn’t increase pain or it actually has a reverse effect and helps relieve pain (this is because super low doses of an antagonist actually increase the sensitivity of the receptor they are supposed to be blocking). That is why a small amount of coffee taken with an opiate/opioid will usually increase its pain killing capacity. However, once you reach a certain point with coffee consumption, the level of opioid receptor antagonists gets so high in your body that you start to experience effects that are very similar to opiate/opioid withdrawal. This will happen even with decaf coffee, because while the caffeine can also cause pain, anxiety and more in higher quantities, it is the opiate antagonists in the coffee itself that cause the most problems when taken in too high of levels, even if decaf. The fact that coffee contains small amounts of MAOI’s also doesn’t help, because the MAOI’s increase the effect and prolong blood levels of the opiate receptor antagonists even more!
When this occurs, the symptoms of inadequate opioid activity include aches all over the body, painful electric sensations throughout the body, anxiety, jitteriness, a flu-like feeling, nausea, headache, and more. People with Borderline Personality Disorder often report that their regular everyday life experience is very similar to mild opioid withdrawal, and their aches and pains coupled with irritability and constant worries or anger is the main reason why such people are so hard to live with, even if they can’t help it that they are naturally that way. Most people with BPD don’t understand the biological mechanisms behind it and so they go untreated or treated with the wrong kind of medicine for their entire lives and don’t know how to fix themselves.
Ok, so now in closing, I’ve covered a lot, I know! It’s important for you to understand, however, that one symptom in your body, like pain, can be caused by any number of variables which are often times little known or too complex to understand without lengthy study, research and trial and error. If you are experiencing chronic pain or pain in absence of a physical injury, or if you are experiencing irritability, anxiety, insomnia, etc, then it may be because of one of the bullet points I discussed above. Sometimes you have to experiment a little bit to find out which thing it is, which thing is the true cause. However, once you figure out what works, it makes it that much easier to treat the issue again the next time it comes along. It also makes it easier to take measures to lessen the likelihood or frequency of those problems occurring again in the future. This is the essence of “Bio Hacking”… its figuring out what chemicals in the body cause what functions, and then learning to manipulate that to our advantage to improve our quality of life!
However, even as you grow in your knowledge of how the body works, you should still go see a doctor if you have any serious or prolonged health problem, and you should keep the knowledge I’ve taught you in mind as supplemental, as a good sized helpful chunk of solving the puzzle, but what you learn from me might not necessarily be able to solve 100% of the puzzle. While I have had many problems with doctors and the medical system in America, I am NOT recommending that you forgo seeking advice or treatment options from a licensed medical professional, even if there are some draw backs or risks involved with that system. You can always choose to turn down a doctor’s suggested treatment or advice, but it’s still good to get their input when you are dealing with a serious health problem, especially one that may require blood work or scans to figure out.
At Bio Hacking Academy, I offer a range of medicinal herb supplements that may offer a wide variety of health benefits. While my products have not been evaluated or approved by the FDA, every one of the ingredients in each of my products has numerous scientific studies and anecdotal evidence available all over the internet and in books, scholarly publications, etc which support the purported health benefits of my products. Some of my products may be useful in remedying some of the issues discussed in this post today. You can click here to access my product catalog, and you may request free samples from me at any time by following the instructions on my Product/Free Sample page or by contacting me through any of the following contact methods below:
Call or Text 704-682-9936 (please say you are calling about Bio Hacking Academy)
Finally, you can go to my Contact page here on this website and send me a message through there.
I am coming up with new formulas on a pretty frequent basis, sometimes as much as a few new formulas per month. Some of them end up not being so good, and I scrap them, while others are winners and keepers. As such, when you request a free sample from me (based upon what’s already listed in my product catalog), I may also include a free sample of one of my new formulas which is not yet listed in the catalog. Because I come up with new formulas so often, I cannot easily update my catalog every time I have a new edition, so I’ll be updating the catalog instead once every couple of months.
Thank you so much for reading, and I hope you’ll check out the rest of the content I have on my site, and I hope you’ll give some of my products a try. My catalog will provide you with instructions on how to place an order me. I also have one on one private coaching available for people who wish to learn more in-depth about the topics I discuss on my website, and who wish to learn how to “Bio Hack” on an advanced level. Sessions are $35 per half hour lesson. Just contact me through one of the methods listed above and ask for a session, and we’ll work something out that fits both of our schedules.
Until next time, may God bless you!
– Joshua Porch, Founder and Owner of Bio Hacking Academy
Ok, so I guess this would be my first real blog post after the introduction. I figured that I should first and foremost explain my goals for and through the Bio Hacking Academy, because it is important that people understand where I’m coming from and how I can help them.
It wasn’t until quite recently that I discovered through x-rays from my Chiropractor (the 3rd one I’d tried) that I have scoliosis and that it appeared to have been juvenile, starting around age 10 or 11, the doctor believes. This is the age that I began experiencing frequent back pain, though I didn’t know the cause. I know now that there is at least one additional cause of my pain aside from the scoliosis, and while I’m still working on figuring it all out, I’ve got a pretty good understanding of the mechanics of it… the muscle and nerve pain that is.
You see, I wasn’t able to see a doctor about my back pain until I was 18 years old (or maybe it was 19) but even when I did go, I spent years and years trying tons of different tests, medicines and non-drug therapies, and almost none of them helped. Over the years, I tried over a dozen medicines for pain, and only opiates worked well. Synthetic cannabinoids and real marijuana worked too but only in doses that were uncomfortably strong, so that wasn’t a realistic option either. I couldn’t get any opiates besides tramadol prescribed for any lengthy period, and even that eventually stopped working well and started causing frequent nausea and vomiting.
After so many years of trial and error, and tons of money from me and my parents flushed down the drain in a broken medical system, I decided that I wanted to try the natural route (for the most part). I had been studying pharmacology and biology and chemistry and psychology for many years up to this point, but I still had a lot to learn to get to the point of knowledge that I’m at today. I had to do lots of testing, using myself as a guinea pig, testing out all sorts of different herbs and a few man-made substances which weren’t illegal through different consumption methods and for different desired effects, all seeking something to kill the pain and ease my mind from the constant stresses of my life. I had many failures, many scary moments where I thought I’d poisoned myself and was thankful when it was all over. It was all because I took too much of something or didn’t know a certain combination would cause a negative reaction. However, through perseverance, research, and God’s divine protection, I kept improving my knowledge of the human body, herbs, drugs, the mind, the spirit, and more while learning how to do all these things more safely.
At some later point, I’ll perhaps go into some of the extreme stresses of my life that I went through as a kid, teenager and even in my 20’s (I’m 29 now). I will say, however, that stress from many circumstances that were out of my control took a huge toll on my health, and I focused heavily on stress, pain, anxiety, depression and insomnia relief options that were all natural, not-too-weak and not-too-strong. Over time, I got better and better at my craft and learned techniques for improving other areas of life like hormonal health (for men that is), muscle building, fat burning, sexual enhancement and cognitive enhancers (AKA “Brain Boosters”). I even made some other cool discoveries that I’ll share some other time.
The point is, I realized over time that I knew more about the functioning of the human body, the functioning of herbs, supplements and nutrition than almost anyone I knew. Only 2 doctors I ever met knew things that I didn’t, at least based upon our discussions. Most of the doctors I visited were 100% ignorant about some medical knowledge that seemed basic and common knowledge to me, something that was vitally important to health but which could be discovered by just a 30 to 60 second search on Google. I have respect for doctors that are truly knowledgable, reasonable and truly care about the patient above and beyond financial manipulation, but I have a strong disdain for doctors that either intentionally mislead or withhold proper info/meds from patients for various corruption reasons. I also have a disdain for doctors who don’t keep up with the latest research in medical advancements, especially as it relates to the pharmacology of the types of medicines they prescribe their patients or whose patients often need.
My mission with the Bio Hacking Academy is to educate people on how the body works, and how to use legal, non-prescription options to manipulate or “HACK” their body and brain chemistry in beneficial ways to enhance and improve their quality of life. My intent is not to persuade people to never go to a doctor or never take any synthetic drug (because sometimes they are necessary), but rather to teach people how to gauge their doctor’s competence, how to figure out what types of medicines are right for you (regardless of what your doctor tries to persuade you to take), and how to find and correctly use natural or select man-made substances and supplements that are available in stores and online, all without a prescription or without someone controlling the size and timing of your dosages, especially when they may not know your body and your health problems as good as you do.
That being said, I am not a licensed healthcare professional (yet) and what I say or type on here or any of my content should not be considered medical or legal advice, but rather an expert opinion from a highly educated researcher who studies advanced scientific research, who does not have the kind of paper certifications that the FDA and like-bodies would require me to have if I wanted to run my own practice. None of my statements on this website, videos or any other content from me have been evaluated by the FDA and none of my advice or herbal products have been FDA approved/proven for the treatment, cure, diagnosis or prevention of any disease or ailment. I teach largely off of anecdotal evidence, a variety of scientific research studies/findings from around the world, and historical uses of certain herbs for certain health problems from various cultures all around the world in ancient and modern times.
I am here to empower individuals to become healthier, happier, smarter and wiser. I have deep and powerful spiritual convictions as well, which I will share in a separate section of my site, so that those who want to hear and know can do so, while those who don’t care to hear about my spiritual beliefs don’t have to watch, listen or read about it. Thanks for reading, and please check out my Products and Samples Page to see the latest info on what I have available. Please also check out my Videos section where I teach various lessons on Bio Hacking (basic and easy to implement stuff) and do herbal product reviews.
If you want to subscribe to my email list, please send me an email through the Contact form and ask for your email address to be added to my list and I will do so, since I can’t set up an email opt-in window on this website right now. I don’t mail often, but when I do, you’ll be the first to be in the know about all things Bio Hacking Academy and health related.
Hey everyone! My name is Joshua Porch, founder of the Bio Hacking Academy, and I’d like to thank you for stopping by and I’d like to welcome you to my website! I have an accompanying Facebook page and YouTube channel, where I’ll be posting videos teaching on a variety of health and science topics, though I will add something else into the mix every now and then.
My aim is to teach people how their bodies work, and how they can utilize foods, herbs, and a few select man-made supplements or drugs to take their quality of life and their performance to the next level, in every area. Better fitness, better intelligence, cognition, and productivity, better love lives (sex, emotional connection, getting along better), and just better health all around… that’s what I aim to teach people through the Bio Hacking Academy!
I’ll be making my first “real” blog post soon, I’m still learning how to use this wordpress theme.
Have a Blessed Day!
“It’s like cheat codes for your body and brain” — Joshua Porch